51571-00-7

Basic information

• Product Name: Benzenamine, 2-chloro-N-hydroxy-5-(trifluoromethyl)-
• CAS NO: 51571-00-7
• Molecular Formula: C7H5ClF3NO
• Molecular Weight: 211.571
• Mol File: 51571-00-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenamine, 2-chloro-N-hydroxy-5-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 2-chloro-N-hydroxy-5-(trifluoromethyl)-(51571-00-7)
• EPA Substance Registry System: Benzenamine, 2-chloro-N-hydroxy-5-(trifluoromethyl)-(51571-00-7)

Safety Data

• Hazardous Substances Data: 51571-00-7(Hazardous Substances Data)

Upstream product

• 121-17-5 2-chloro-3-nitro-5-trifluoromethylbenzene 

Downstream Products

• 51571-02-9 4,5-dichloro-2-(trifluoromethyl)phenol 
• 51570-99-1 2-Aminomethyl-3,4-dichloro-6-trifluoromethyl-phenol; hydrochloride 
• 67119-54-4 2-Chlor-5-trifluormethyl-nitrosobenzol 
• 51571-01-8 4-amino-3-chloro-6-(trifluoromethyl)phenol 

Relevant articles and documents

Regioselective installation of fluorosulfate (-OSO2F) functionality into aromatic C(sp2)-H bonds for the construction of: Para-amino-arylfluorosulfates

The construction of para-amino-arylfluorosulfates was achieved through installation of fluorosulfate (-OSO2F) functionality into aromatic C(sp2)-H bonds by the reaction of N-arylhydroxylamine with sulfuryl fluoride (SO2Fs

Trifluoromethoxylation of arenes: Synthesis of ortho- Trifluoromethoxylated aniline derivatives by OCF3 migration

Aryl trifluoromethoxylation by a two-step sequence of O-trifluoromethylation of N-aryl-N-hydroxylamine derivatives and intramolecular OCF3 migration is presented. This protocol allows easy access to a wide range of synthetically useful ortho-OCF3 aniline derivatives. In addition, it utilizes bench-stable reagents, is operationally simple, shows high functional-group tolerance, and is amenable to gram-scale as well as one-pot synthesis.Areaction mechanism of a heterolytic cleavage of the N-OCF3 bond followed by recombination of the resulting nitrenium ion and trifluoromethoxide is proposed for the OCF3-migration reaction.