51572-92-0

Usage

Uses

Used in Pharmaceutical Industry:
1-[(Ammoniooxy)methyl]-2-nitrobenzene chloride is used as a reagent and intermediate for the synthesis of various pharmaceuticals, playing a crucial role in the development of new medications and the improvement of existing ones. Its reactivity allows for the creation of a wide range of chemical compounds that can be utilized in the treatment and management of various health conditions.
Used in Dye and Pigment Production:
In the dye and pigment industry, 1-[(Ammoniooxy)methyl]-2-nitrobenzene chloride is employed as a key component in the production of various dyes and pigments. Its chemical properties enable the creation of a diverse array of colorants that are used in different applications, such as textiles, plastics, and printing inks.
Used in Industrial Chemical Synthesis:
1-[(AMMONIOOXY)METHYL]-2-NITROBENZENE CHLORIDE is also utilized in the synthesis of other industrial chemicals, where its reactivity and versatility contribute to the development of new chemical products and processes. Its applications in this field can range from the production of specialty chemicals to the enhancement of existing industrial processes.

InChI:InChI=1/C7H8N2O3.ClH/c8-12-5-6-3-1-2-4-7(6)9(10)11;/h1-4H,5,8H2;1H

Upstream product

• 36663-91-9 2-nitrobenzyl benzohydroxamate 

Relevant academic research and scientific papers

1-ALKOXY 1H-IMIDAZO RING SYSTEMS AND METHODS

Imidazo-containing compounds (e.g., imidazonaphthyridines, imidazopyridines, imidazoquinolines, and imidazotetrahydroquinolines) with an alkoxy substituent at the 1-position, pharmaceutical compositions containing the compounds and methods of use of these

ESTRATRIENE DERIVATIVES

Compounds and methods for modulating mesenchymal cell function, for instance smooth muscle and fibroblast proliferation or cytokine expression, and for treating conditions associated with mesenchymal cell function, for instance airway hyperresponsiveness

New calcium antagonists: Synthesis, X-ray analysis, and smooth muscle relaxing effect of 3-[O-(benzyl-substituted)-oximino-ethers]-hexahydroazepin-2,3-diones

A series of new Z and E 3-[O-(benzyl-substituted)-oximino-ether]-hexahydroazepin-2,3-diones was prepared from the corresponding hexahydroazepin-2,3-diones and examined as smooth muscle relaxants. E and Z structures were assigned by NMR analysis and confirmed for 16 (E and Z) by an X-ray diffraction using synchrotron radiations. The nitrobenzyl derivative 16 was the most potent in vitro as relaxant of rat trachea precontracted with acetylcholine. The E isomer 16b was more potent than the Z isomer 16a. E isomer 16b is more potent than aminophylline to relax both rat trachea and human bronchus.This derivative acts mainly by inhibiting cellular infux of extracellular calcium since it inhibits potently and dose-dependently the contractions of rat trachea to high concentrations of KCl and to CaCl2 in a depolarizing medium. It appears to act weakly by inducing cGMP and cAMP synthesis. Moreover, its relaxing activity is not related to an inhibition of phosphodiesterases, to opening of potassium channels or to induction of prostaglandin synthesis. Therefore, 16b appears to work mainly as a potent calcium antagonist. (C) 1999 Elsevier Science Ltd.