51577-39-0

Upstream product

• 292638-85-8 acrylic acid methyl ester 
• 108-94-1 cyclohexanone 
• 10407-33-7 methyl 3-(2-oxocyclohexyl)propionate 
• 1125-99-1 1-(1-Cyclohexen-1-yl)pyrrolidine 
• 56146-64-6 2-(p-toluenesulfinyl)-cyclohexanone 
• 83135-28-8 allyl 1-<2-(methoxycarbonyl)ethyl>-2-oxocyclohexanecarboxylate 
• 700-82-3 3,4,5,6,7,8-hexahydro-chromen-2-one 

Downstream Products

• 1106986-99-5 5-oxo-3-phenyl-2,3,5,6,7,7a,10,11-octahydrooxazolo[2,3-j]quinoline 
• 1106986-40-6 (3R,7aS,11aS)-5-oxo-3-phenyl-2,3,5,6,7,7a,10,11-octahydrooxazolo[2,3-j]quinoline 
• 380605-67-4 5-(2-methyl-6-oxo-cyclohexyl)-pent-2-ynoic acid methyl ester 
• 323577-60-2 3-(2-methyl-6-oxo-cyclohexyl)-propionaldehyde 

Relevant academic research and scientific papers

A practical synthetic route to enantiopure 6-substituted cis-decahydroquinolines

Starting from 4-substituted cyclohexanones, a practical synthetic route to enantiopure 6-substituted cis-decahydroquinolines has been developed, the key steps being a stereoselective cyclocondensation of an unsaturated δ-keto ester derivative with (R)-phenylglycinol and the stereoselective hydrogenation of the resulting tricyclic oxazoloquinolone lactams.

α-Thiosubstituted chiral imines/secondary enamines: Their use in the asymmetric Michael reaction

The asymmetric Michael reaction between 2-thiosubstituted chiral imines/secondary enamines derived from (S)-1-phenylethylamine and electrophilic alkenes (methyl acrylate, MVK) was investigated. 2-Phenylthio derivatives furnished the expected Michael adducts with excellent ee. By contrast, an in situ elimination of p-toluenesulfenic acid took place when using the p-toluenesulfinyl analogs. Copyright (C) 2000 Elsevier Science Ltd.