51582-41-3

Usage

Chemical Properties

Yellow Solid

InChI:InChI=1/C15H13NO4/c17-16(18)13-8-12(15-10-20-15)6-7-14(13)19-9-11-4-2-1-3-5-11/h1-8,15H,9-10H2

Upstream product

• 299964-35-5 (+/-)-2-bromo-1-(4-benzyloxy-3-nitrophenyl)ethanol 
• 99-93-4 4-Hydroxyacetophenone 
• 6322-56-1 4'-hydroxy-3'-nitroacetophenone 
• 43229-01-2 4-benzyloxy-3-nitrophenacyl bromide 
• 14347-05-8 4-benzyloxy-3-nitroacetophenone 

Downstream Products

• 1028681-14-2 C₃₁⁽¹³⁾CH₂₅⁽²⁾H₉N₂O₅ 
• 43229-67-0 1-(4-benzyloxy-3-nitrobenzene)-2-{benzyl-[2-(4-methoxyphenyl)-1-methylethyl]amino}ethanol 
• 169375-55-7 formoterol fumarate 
• 128954-45-0 formoterol 
• 1068147-87-4 tert-butyl 6-(benzyl(2-(4-(benzyloxy)-3-nitrophenyl)hydroxyethyl)amino)hexylcarbamate 
• 1068147-86-3 tert-butyl 4-(benzyl(2-(4-(benzyloxy)-3-nitrophenyl)hydroxyethyl)amino)butylcarbamate 
• 1068147-85-2 tert-butyl 2-(benzyl(2-(4-(benzyloxy)-3-nitrophenyl)hydroxyethyl)amino)ethylcarbamate 
• 1068147-88-5 tert-butyl 2-(2-(2-(benzyl(2-(4-(benzyloxy)-3-nitrophenyl)hydroxyethyl)amino)ethoxy)ethoxy)ethylcarbamate 
• 876753-53-6 N-(2-benzyloxy-5-vinylphenyl)formamide 
• 515152-69-9 2-benzyloxy-5-vinylnitrobenzene 
• 876753-52-5 2-benzyloxy-5-vinylaniline 

Relevant academic research and scientific papers

Synthesis of N-[2-benzyloxy-5-(2-oxiranyl)-phenyl]formamide: Formal synthesis of formoterol

Nitration, benzylation followed by bromination of 4- hydroxyacetophenone is described to obtain nitrobenzyloxyphenacyl bromide derivative 3. Sodiumborohydride reduction of 3 gives rise to the diol 6. Reaction of 6 with Ph3P/I2/imidaz

2-(3-Benzyloxy-4-nitrophenyl)oxirane, an Intermediate in the Synthesis of Formoterol

In the title compound, C15H13NO4, the two planar nitrophenyl and benzyloxy groups are inclined at 152.3(2) deg.The torsion angle about the central C-O bond is 177.5(5) deg, giving an extended C-C-O-C chain.The nitro group is twisted out of the plane of the phenyl ring by 28.4(3) deg to diminish steric hindrance; O atoms of the nitro and benzyloxy groups are separated by only 2.625(7) Angstroem.The dihedral angles between the epoxy ring and the two aromatic rings are 98.3(3) and 102.6(3) deg.There is a possible C-H...O intermolecular interaction.

Bronchospasmolytic phenylethanolamines

Phenylethanolamines of the formula I STR1 wherein R is substituted phenyl or optionally substituted furyl, thienyl, or pyridyl, R5 is hydrogen, lower alkyl, or optionally substituted benzyl, R4, R6, R8, and Rsu