51584-17-9 Usage
Uses
Used in Pharmaceutical Research:
1-Methylindole-3-acetonitrile is used as a substrate in pharmaceutical research for the enzyme indoleamine 2,3-dioxygenase, contributing to the understanding of immune response regulation and potentially aiding in the development of new drugs.
Used in Organic Synthesis:
1-Methylindole-3-acetonitrile is utilized as a building block in the synthesis of organic compounds, playing a crucial role in the creation of various chemical entities for different applications.
Used in Drug Development:
1-Methylindole-3-acetonitrile is employed in the development of new drugs, leveraging its biological activities and chemical properties to contribute to the discovery and design of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 51584-17-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,5,8 and 4 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 51584-17:
(7*5)+(6*1)+(5*5)+(4*8)+(3*4)+(2*1)+(1*7)=119
119 % 10 = 9
So 51584-17-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H10N2/c1-13-8-9(6-7-12)10-4-2-3-5-11(10)13/h2-5,8H,6H2,1H3
51584-17-9Relevant academic research and scientific papers
Synthesis of Indole Derivatives from N-Alkenyl-o-chloroanilines with Zero-valent Nickel Complex
Rodriguez, J. G.,Canoira, L.
, p. 883 - 888 (2007/10/02)
Reaction of N-alkenyl-o-chloroanilines in toluene with tetrakis(triphenylphosphine)nickel(0) was carried out mainly to give indole and indoline derivatives in good yields.A detailed analysis of the reaction products has been done and it allows us to confirm the postulated mechanism of the cyclization reaction.Torsional hindrance around C-C-Csp2 bond seems to prevent the cyclization reaction.
