515871-89-3Relevant academic research and scientific papers
Orthopalladated complexes as phase-transfer catalysts for asymmetric alkylation of achiral Schiff base esters
Kim, Dae Hyun,Im, Jin Kyu,Kim, Dae Won,Lee, Hyunjoo,Kim, Honggan,Kim, Hoon Sik,Cheong, Minserk,Mukherjee, Deb Kumar
, p. 949 - 957 (2010)
The asymmetric C-alkylation of benzophenone Schiff base glycine esters has been achieved using a palladium(II) chiral complex as a phase-transfer catalyst. The aromatic moiety around the metal center and various physicochemical parameters were investigated to study their effect on the asymmetric alkylation reaction under phase-transfer conditions. Moderate enantioselectivity(30-40%) was achieved under room temperature conditions, which is a significant improvement compared to no enantioselectivity with a chiral palladium-salen complex reported earlier. Computer simulation studies indicate that coordination of the metal center with Z-enolate forming a square planar complex provides a favorable steric environment where the α-carbon atom of the enolate is available for enantioselective alkylation.
Improved access to chiral tetranaphthoazepinium-based organocatalysts using aqueous ammonia as nitrogen source
Manaprasertsak, Auraya,Tharamak, Sorachat,Schedl, Christina,Roller, Alexander,Widhalm, Michael
supporting information, (2019/11/05)
The class of 3,30-diaryl substituted tetranaphthobisazepinium bromides has found wide application as highly efficient C2-symmetrical phase-transfer catalysts (PTCs, Maruoka type catalysts). Unfortunately, the synthesis requires a lar
