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Milbemycin A3 is a member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group. It is produced from the fermentation of the soil bacterium S. hygroscopicus subsp. aureolacrimosus. As a compound that potentiates glutamate and GABA-gated chloride-channel opening, Milbemycin A3 is a highly selective and potent nematocide and insecticide.
Used in Agriculture:
Milbemycin A3 is used as a pesticide for controlling various nematodes and insects that damage crops. It is particularly effective against adult spider mites, spider mite eggs, and C. elegans, with reported IC50 values of 5.3, 41.1, and 9.5 μg/ml, respectively.
Used in Veterinary Medicine:
Milbemycin A3 is used as an antibiotic with acaricidal activity, helping to treat and prevent parasitic infections in animals. Its selective action on chloride-gated ion channels makes it an effective treatment for various parasitic infestations.

51596-10-2

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51596-10-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 51596-10-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,5,9 and 6 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 51596-10:
(7*5)+(6*1)+(5*5)+(4*9)+(3*6)+(2*1)+(1*0)=122
122 % 10 = 2
So 51596-10-2 is a valid CAS Registry Number.

51596-10-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name milbemycin A3

1.2 Other means of identification

Product number -
Other names milbemycin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:51596-10-2 SDS

51596-10-2Upstream product

51596-10-2Relevant academic research and scientific papers

Total synthesis of the spiroketal macrolide (+) milbemycin α1

Ley, Steven V.,Madin, Andrew,Monck, Nathaniel J. T.

, p. 7479 - 7482 (1993)

The total synthesis of the antiparasitic spiroketal macrolide (+) milbemycin α1 is reported, following Julia sulfone anion coupling of the sulfone 3 with a northern hemisphere aldehyde 2 and subsequent functional group elaboration.

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