51607-12-6Relevant academic research and scientific papers
Synthesis and pharmacological evaluation of 5-pyrrolidinylquinoxalines as a novel class of peripherally restricted κ-opioid receptor agonists
Bourgeois, Christian,Werfel, Elena,Galla, Fabian,Lehmkuhl, Kirstin,Torres-Gómez, Héctor,Schepmann, Dirk,K?gel, Babette,Christoph, Thomas,Stra?burger, Wolfgang,Englberger, Werner,Soeberdt, Michael,Hüwel, Sabine,Galla, Hans-Joachim,Wünsch, Bernhard
, p. 6845 - 6860 (2014)
5-Pyrrolidinyl substituted perhydroquinoxalines were designed as conformationally restricted κ-opioid receptor agonists restricted to the periphery. The additional N atom of the quinoxaline system located outside the ethylenediamine κ pharmacophore allows
