51608-67-4Relevant academic research and scientific papers
Alpha-substituted benzhydrol derivatives
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, (2008/06/13)
The invention relates to new α-substituted benzhydrols and pharmaceutically acceptable acid addition salts or quaternary ammonium salts thereof with enzyme promoting or inhibiting effects;
α-Substituted benzhydrol derivatives and a process for the preparation thereof
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, (2008/06/13)
A compound of the formula: STR1 wherein Z is ethyl or vinyl, R1 and R2 are hydrogen, lower alkyl, lower alkenyl or trihalomethyl, R3 and R4 are hydrogen, lower alkyl, lower alkenyl, trihalomethyl, cyclopentyl, benzyl or phenyl, and R5 is lower alkyl, lower alkenyl, trihalomethyl, cyclopentyl, benzyl, or phenyl with the proviso that where R1, R2, R3 and R4 each is hydrogen, R5 is not methyl attached to the 4-position of the benzene ring, or a pharmaceutically acceptable acid addition or quaternary ammonium salt thereof is disclosed as effective in the regulation of the liver microsomal enzyme system.
