5164-41-0Relevant academic research and scientific papers
Surface-mediated Solid Phase Reaction. Part 6. Mukaiyama-Michael Addition of Silyl Ethers to Alkyl Vinyl Ketones on the Surface of Alumina: a Simple and Convenient Method for the Synthesis of 1,5-Diketones
Ranu, Brindaban C.,Saha, Manika,Bhar, Sanjay
, p. 2197 - 2200 (2007/10/02)
Michael addition of silyl enol and dienol ethers to alkyl vinyl ketones occurs in high yields through a simple solvent-free reaction on the surface of anhydrous zinc chloride-impregnated alumina to give 1,5-diketones.
New Effective Catalysts for Mukaiyama-Aldol and -Michael Reactions: BiCl3 - Metallic Iodide Systems
Roux, Christophe Le,Gaspard-Iloughmane, Hafida,Dubac, Jacques,Jaud, Joel,Vignaux, Pierre
, p. 1835 - 1839 (2007/10/02)
Metallic iodide-activated bismuth(III) chloride efficiently catalyzes the Mukaiyama-Aldol and -Michael reactions.Some examples of reactions of silyl enol ethers derived from acetophenone and cyclohexanone (1 and 2, respectively) with aldehydes, ketones, a
Organotin Triflate as Practical Catalyst for Michael Addition of Enol Silyl Ethers
Sato, Tsuneo,Wakahara, Yoshiyuki,Otera, Junzo,Nozaki, Hitosi
, p. 9773 - 9782 (2007/10/02)
Dibutyltin bis(triflate) is a mild Lewis acid which catalyzes clean Michael addition of enol silyl ethers.The new catalyst allows to employ various labile acceptors such as methyl vinyl ketone and 2-cyclopentenone which do not undergo smooth reaction with
Organotin triflates as functional Lewis acids. A new entry to simple and efficient Robinson annulation
Sato, Tsuneo,Wakahara, Yoshiyuki,Otera, Junzo,Nozaki, Hitosi
, p. 1581 - 1584 (2007/10/02)
An efficient Robinson annulation has been established through the Michael addition of enol silyl ethers to α-enones catalyzed by dibutyltinbis(triflate) followed by the MeONa-mediated intramolecular aldol condensation of the adducts.
REGIOSELECTIVE HYDRATION OF ALKYNONES BY PALLADIUM CATALYSIS
Imi, Katsuharu,Imai, Kumiko,Utimoto, Kiitiro
, p. 3127 - 3130 (2007/10/02)
Diketones are regioselectively prepared from alkynyl ketones under mild conditions by palladium catalysis; 5-heptyn-2-one and 2-(2-nonynyl)cyclohexanone give 1,4-diketones whereas 2-(2-heptynyl)cyclopentanone and 5,6-didehydroprostaglandin E2 methyl ester afford 1,5-diketones.
