51646-44-7

Upstream product

• 51646-43-6 2-benzylsulfanyl-7-oxo-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester 
• 3922-47-2 3-(benzylthio)-1H-1,2,4-triazol-5-amine 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 

Downstream Products

• 51646-45-8 2-benzylsulfanyl-7-morpholin-4-yl-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester 
• 51646-48-1 2-benzylsulfanyl-7-(2-hydroxy-ethylamino)-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester 
• 51646-47-0 2-benzylsulfanyl-7-propylamino-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester 
• 51646-46-9 7-benzylamino-2-benzylsulfanyl-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester 
• 51646-49-2 2-benzylsulfanyl-7-thioxo-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

2-(Alkylthio)-1,2,4-triazolo[1,5-a]pyrimidines as adenosine cyclic 3',5'-monophosphate phosphodiesterase inhibitors with potential as new cardiovascular agents

A series of new 2-(alkylthio)-5,7-disubstituted-1,2,4-triazolo[1,5-a]pyrimidines have been prepared as inhibitors of cAMP phosphodiesterase from various tissues. These derivatives were prepared via ring closure of various requisite 3-amino-1,2,4-triazole

2-SUBSTITUTED-S-TRIAZOLO[1,5A]-PYRIMIDINES

2-Substituted-s-triazolo[1,5a]pyrimidines are disclosed which are useful as inhibitors of phosphodiesterase enzymes or intermediates in the production process. Such comoounds are of the following structure: wherein X, R, R1, R2 and R3 are as defined herei