5165-50-4

Upstream product

• 141-97-9 ethyl acetoacetate 
• 104-94-9 4-methoxy-aniline 
• 106-51-4 p-benzoquinone 
• 201990-83-2 ethyl β-(p-methoxyphenylamino)crotonate 

Downstream Products

• 134826-49-6 5-(3-Cyano-pyridin-2-yloxy)-1-(4-methoxy-phenyl)-2-methyl-1H-indole-3-carboxylic acid ethyl ester 
• 136038-65-8 1-(4-Methoxy-phenyl)-2-methyl-5-(5-nitro-6-piperidin-1-yl-pyrimidin-4-yloxy)-1H-indole-3-carboxylic acid ethyl ester 
• 136038-67-0 5-(6-Methoxy-5-nitro-pyrimidin-4-yloxy)-1-(4-methoxy-phenyl)-2-methyl-1H-indole-3-carboxylic acid ethyl ester 
• 134826-58-7 5-(3,5-Dicyano-4-phenylamino-pyridin-2-yloxy)-1-(4-methoxy-phenyl)-2-methyl-1H-indole-3-carboxylic acid ethyl ester 
• 134826-55-4 5-[3-Cyano-4-(4-methoxy-phenylamino)-pyridin-2-yloxy]-1-(4-methoxy-phenyl)-2-methyl-1H-indole-3-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Montmorillonite clay catalyzed three component, one-pot synthesis of 5-Hydroxyindole derivatives

A highly efficient and environmentally benign protocol has been developed for the first time to produce a wide range of biologically active 5-hydroxyindole derivatives using montmorillonite KSF clay as a reusable solid acid catalyst. The use of recyclable clay makes this procedure quite simple, more convenient and cost-effective.

Synthesis and biological screening of some new novel indole derivatives

Synthesis of some novel indole derivatives has been undertaken by the reaction of 1,4-benzoquinone with ethyl-β-(arylamino)-crotonates in the presence/absence of nitrogen atmosphere. The products 1a-o have been screened for their antimicrobial activity an