5165-81-1

Basic information

• Product Name: naphthol AS-RS
• Synonyms: naphthol AS-RS;N-(4-chloro-2-methoxy-5-methylphenyl)-3-hydroxy-2-naphthamide;N-(4-chloro-2-methoxy-5-methylphenyl)-3-hydroxy-2-Naphthalenecarboxamide;2-Naphthalenecarboxamide, N-(4-chloro-2-methoxy-5-methylphenyl)-3-hydroxy;C.I.Azoic Coupling Component 28;Naphtanilide RS;Naphtol AS-RS.;C.I.37541
• CAS NO: 5165-81-1
• Molecular Formula: C₁₉H₁₆ClNO₃
• Molecular Weight: 341.78824
• EINECS: 225-946-3
• Mol File: 5165-81-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 458.9°Cat760mmHg
• Flash Point: 231.4°C
• Appearance: /
• Density: 1.35g/cm³
• PKA: 8.68±0.40(Predicted)
• CAS DataBase Reference: naphthol AS-RS(CAS DataBase Reference)
• NIST Chemistry Reference: naphthol AS-RS(5165-81-1)
• EPA Substance Registry System: naphthol AS-RS(5165-81-1)

Safety Data

• Hazardous Substances Data: 5165-81-1(Hazardous Substances Data)

Usage

Preparation

4-Chloro-2-methoxy-5-methylbenzenamine?in pyridine with?N-(4-chloro-2-methoxy-5-methylphenyl)-3-hydroxy-2-naphthamide condensation.

Properties and Applications

Shallow brown powder, insoluble in water. Mainly used for cotton, PVA?dyeing and glue, and all the good fastness, not used for printing of cotton. To cotton of high affinity.

Upstream product

• 92-70-6 3-Hydroxy-2-naphthoic acid 
• 6376-14-3 2-methoxy-5-methyl-4-chloroaniline 

Relevant articles and documents

Fluorescent substrates for potential use in enzyme-linked immunosorbent assay of membrane-bound nucleic acids

A number of phosphorylated fluorochromes were synthesized and tested for the alkaline phosphatase-linked fluorescence assay of membrane-bound nucleic acids. 3-Hydroxy-N-2′-biphenyl-2-naphthalenecarboxamide phosphate ester (HBNP) was found to be the most suitable for the assay. Nonfluorescent HBNP is hydrolyzed by phospholipase bound to the probe DNA to the highly fluorescent 3-hydroxy-N,2′-biphenyl-2-naphthalenecarboxamide (HBN). HBN is insoluble enough in aqueous medium to precipitate on the nylon membrane. Spots containing as little as 5 fg of λ DNA can be successfully detected on the membrane with HBNP.