51677-40-8

Basic information

• Product Name: 4-(1-Azido-1-methylethyl)-1,1'-biphenyl
• Synonyms: 4-(1-Azido-1-methylethyl)-1,1'-biphenyl
• CAS NO: 51677-40-8
• Molecular Formula: C15H15N3
• Molecular Weight: 0
• Mol File: 51677-40-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(1-Azido-1-methylethyl)-1,1'-biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1-Azido-1-methylethyl)-1,1'-biphenyl(51677-40-8)
• EPA Substance Registry System: 4-(1-Azido-1-methylethyl)-1,1'-biphenyl(51677-40-8)

Safety Data

• Hazardous Substances Data: 51677-40-8(Hazardous Substances Data)

Upstream product

• 7116-95-2 4-isopropylbiphenyl 
• 34352-74-4 2-biphenyl-4-yl-propan-2-ol 
• 34352-84-6 4-(propen-2-yl)biphenyl 

Relevant articles and documents

Site-Selective Copper-Catalyzed Azidation of Benzylic C-H Bonds

Site selectivity represents a key challenge for non-directed C-H functionalization, even when the C-H bond is intrinsically reactive. Here, we report a copper-catalyzed method for benzylic C-H azidation of diverse molecules. Experimental and density functional theory studies suggest the benzyl radical reacts with a CuII-azide species via a radical-polar crossover pathway. Comparison of this method with other C-H azidation methods highlights its unique site selectivity, and conversions of the benzyl azide products into amine, triazole, tetrazole, and pyrrole functional groups highlight the broad utility of this method for target molecule synthesis and medicinal chemistry.

Substituted aminoalkyl biphenyl compounds and method of treating fungal infections

Antimycotically-active compounds of the formula STR1 wherein R1 and R2 each independently are hydrogen, C1-7 -alkyl or C2-7 -alkenyl or together are a straight chain C2-4 -alkylene; R3 and R4 each independently are hydrogen or C1-7 -alkyl; R5 and R6 each independently are hydrogen, halogen, trifluoromethyl, nitro, cyano, C1-7 -alkoxy or C1-7 -alkyl; and Q is an unsubstituted or substituted phenyl or naphthyl group, wherein the substituents are at least one of halogen, trifluoromethyl, cyano, nitro, C1-7 -alkyl, C1-7 -alkoxy; C2-10 -alkenyl; or a substituted or unsubstituted C1-10 -alkyl group wherein said substituents are at least one hydroxy group; and pharmaceutically acceptable acid addition salts thereof.