51719-66-5Relevant academic research and scientific papers
Regioisomerism in the synthesis of a chiral aminotetralin drug compound: Unraveling mechanistic details and diastereomer-specific in-depth NMR investigations
Schuisky, Peter,Federsel, Hans-Juergen,Tian, Wei
experimental part, p. 5503 - 5514 (2012/09/07)
During chemical process development of a novel 2-aminotetralin derivative intended for use as an antidepressant, scrutiny of the byproduct present in the drug molecule revealed a set of regioisomers. Detailed studies showed that this impurity issue origin
SPIRO IMIDAZOLE DERIVATIVES AS PPAR MODULATORS
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Page/Page column 42-43, (2008/06/13)
The invention provides compounds (Ia), (Ib) and (Ic), pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated
