51725-83-8Relevant academic research and scientific papers
Synthesis and herbicidal evaluation of novel 3-[(α-hydroxy- substituted)benzylidene]pyrrolidine-2,4-diones
Zhu, Youquan,Zou, Xiaomao,Hu, Fangzhong,Yao, Changsheng,Liu, Bin,Yang, Huazheng
, p. 9566 - 9570 (2007/10/03)
A series of 3-[(α-hydroxy-substituted) benzylidene]pyrrolidine-2,4- dione derivatives were synthesized as candidate herbicides by reacting different aroyl acetates with N-substituted glycine esters. The new compounds were identified by 1H NMR spectroscopy and elemental analyses. Their herbicidal activities were evaluated. Some compounds exhibited excellent herbicidal activities at a dose of 187.5 g/ha. A suitable electron-donating substituent at the 2- and/or 4-position of the phenyl ring was essential for high herbicidal activity, a result that has not been reported before. It was also found that the title compound's structure-activity relationships were different from those of other similar kinds of earlier compounds, a result that may depend on the enol structure difference.
