51726-79-5Relevant academic research and scientific papers
Synthesis of 1,4-Dihydro-4-oxo-quinoline-3-carboxylic Acid Derivatives as Inhibitors of Rat Lens Aldose Reductase
Bueyuekbingoel, Erdem,Das, Net,Klopman, Gilles
, p. 129 - 132 (1994)
The title compounds were prepared according to Scheme 2 and tested as inhibitors of the aldose reductase of rat lens.
Polysubstituted quinolone compounds, and preparation method and use thereof
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Paragraph 0131; 0132; 0133; 0331; 0332; 0333, (2017/09/19)
The invention provides polysubstituted quinolone compounds, and a preparation method and a use thereof, and concretely provides a polysubstituted quinolone compound represented by formula I, and optical isomers, pharmaceutically acceptable salts or solvates thereof. All groups in the formula I are defined in the description. The quinolone compound has excellent c-Met inhibition activity, and can be used for treating c-Met activity or expression level corrected diseases.
