51748-01-7

Basic information

• Product Name: Benzonitrile, 4-chloro-3-hydroxy-
• Synonyms: Benzonitrile, 4-chloro-3-hydroxy-;4-Chloro-3-hydroxybenzonitrile;2-Chloro-5-cyanophenol
• CAS NO: 51748-01-7
• Molecular Formula: C7H4ClNO
• Molecular Weight: 153.57
• Mol File: 51748-01-7.mol

Chemical Properties

• Boiling Point: 254.0±25.0 °C(Predicted)
• Appearance: /
• Density: 1.41±0.1 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 7.11±0.10(Predicted)
• CAS DataBase Reference: Benzonitrile, 4-chloro-3-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 4-chloro-3-hydroxy-(51748-01-7)
• EPA Substance Registry System: Benzonitrile, 4-chloro-3-hydroxy-(51748-01-7)

Safety Data

• Hazardous Substances Data: 51748-01-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Benzonitrile, 4-chloro-3-hydroxy-, serves as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, Benzonitrile, 4-chloro-3-hydroxy-, is utilized as an intermediate for the production of agrochemicals, contributing to the development of effective pesticides and other agricultural products.
Used in Organic Chemistry Research:
Benzonitrile, 4-chloro-3-hydroxy-, is also used as a building block for the synthesis of other complex organic molecules in research settings. Its presence in various chemical reactions can lead to the discovery of new compounds with diverse applications.
Safety Precautions:
It is crucial to handle Benzonitrile, 4-chloro-3-hydroxy-, with care due to its potential toxicity and harmful effects on human health and the environment. Proper safety measures should be taken during its production, use, and disposal to minimize any adverse impacts.

Upstream product

• 748101-41-9 zinc cyanide 
• 183802-98-4 5-bromo-2-chlorophenol 

Relevant articles and documents

Concise synthesis of 6-cyanobenzo[ b ]furan, a useful building block

A new three-step synthesis of 6-cyanobenzo[b]furan (6) was developed, starting from commercially available 6-hydroxybenzo[b]furan-3-one (18). Key steps in this process were the first step, which was the reductive dehydration of 18 to produce 6-hydroxybenzo[b]furan (19), and the last step, which converted the aryl triflate 20 to the aryl cyanide 6 in a palladium-catalyzed cross-coupling protocol. Overall yield for this new synthesis was 49%.

2-PHENOXY NICOTINE ACID DERIVATIVE AND USE THEREOF

The present invention relates to novel 2-phenoxy-6-phenyl- and 2-phenoxy-6-pyridylnicotinic acid derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prophylaxis of cardiovascular disorders, especially of dyslipidemias, arteriosclerosis and heart failure.