51764-98-8

Basic information

• Product Name: (Z)-3-[2-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-2-methyl-propenol
• CAS NO: 51764-98-8
• Molecular Weight: 279.379
• Mol File: 51764-98-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-3-[2-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-2-methyl-propenol(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-3-[2-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-2-methyl-propenol(51764-98-8)
• EPA Substance Registry System: (Z)-3-[2-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-2-methyl-propenol(51764-98-8)

Safety Data

• Hazardous Substances Data: 51764-98-8(Hazardous Substances Data)

Upstream product

• 153991-51-6 3-(2-hydroxyphenyl)-2-methylprop-2-en-1-ol 
• 75-31-0 isopropylamine 

Relevant articles and documents

β-Adrenergic blocking agents. 20. (3-Hydroxyprop-1-enyl)-substituted 1-(aryloxy)-3-(alkylamino)propan-2-ols

The synthesis of a series (3-hydroxyprop-1-enyl)-substituted 1-(aryloxy)-3-(alkylamino)propan-2-ols is described. These compounds were investigated for their β-adrenoreceptor blocking properties and their selectivity of action. Among the o-(hydroxypropenyl)-substituted derivatives the authors have found some potent noncardioselective β-adrenoreceptor blocking agents which have a greater blocking action on the β2 receptor, thus resembling propanolol. The p-(hydroxypropenyl)-substituted analogues were generally less potent and tended to be cardioselective. The structure-activity relationships are discussed in the light of the hypothesis that the cardioselectivity of p-amido-substituted (aryloxy)propanolamines is attributable, in part, to binding of the amide group to some additional site on the β receptor; these findings argue against a similar interaction for the allylic hydroxyl group.