51779-58-9

Basic information

• Product Name: dimethyl 6-methyl-2-phenyl-3,4-pyridinedicarboxylate
• Synonyms: dimethyl 6-methyl-2-phenyl-3,4-pyridinedicarboxylate
• CAS NO: 51779-58-9
• Molecular Formula: C16H15NO4
• Molecular Weight: 285.2946
• Mol File: 51779-58-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: dimethyl 6-methyl-2-phenyl-3,4-pyridinedicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 6-methyl-2-phenyl-3,4-pyridinedicarboxylate(51779-58-9)
• EPA Substance Registry System: dimethyl 6-methyl-2-phenyl-3,4-pyridinedicarboxylate(51779-58-9)

Safety Data

• Hazardous Substances Data: 51779-58-9(Hazardous Substances Data)

Upstream product

• 1008-75-9 3-methyl-5-phenylisoxazole 
• 762-42-5 dimethyl acetylenedicarboxylate 

Relevant articles and documents

Hexacarbonylmolybdenum-induced Reaction of Isoxazoles. Cycloaddition of Isoxazoles with Acetylenic Esters and Related Reactions

In the presence of hexacarbonylmolybdenum, substituted isoxazoles undergo a cycloaddition reaction with dimethyl acetylenedicarboxylate across the C-4-C-5 bond to give 3,4-bis(methoxycarbonyl)pyridine derivatives.In a similar cycloadition of isoxazoles with methyl propiolate, 4-(methoxycarbonyl)pyridine derivatives were also obtained.The β-carbon atom of methyl propiolate could intervene in the bonding with the C-5 position of the isoxazoles regioselectively.A mechanism involving a complexed 2-oxa-3-azabicyclohepta-3,6-diene derivative and the subsequent N-Oand C-1-C-5 bond cleavage leading to a complexed (β-ketovinyl)nitrene intermediate is proposed for the formation of pyridine derivatives.In order to clarify the mechanistic aspect, the reaction of 4-phenyl-2-oxa-3-azabicyclohepta-3,6-diene and its related compounds were also studied to give pyridine derivatives.