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• 462-80-6 benzyne 
• 142128-23-2 (S,E)-ethyl 2-(benzylideneamino)propanoate 
• 1202458-03-4 C₁₆H₁₃NO 

Relevant academic research and scientific papers

Geometry-dependent divergence in the gold-catalyzed redox cascade cyclization of o-alkynylaryl ketoximes and nitrones leading to isoindoles

We report geometry-dependent cyclizations of o-alkynylaryl ketoximes and nitrones catalyzed by gold complexes. (E)-Ketoximes undergo N-attack to give isoquinoline-N-oxides. In sharp contrast, (Z)-ketoximes undergo unprecedented O-nucleophilic attack, foll

Competitive 3+2 and 2+2 cycloadditions of ester stabilized azaallyl anions to benzynes. Ring expansion of initial 3+2 products to isoquinolin-3-ones

Reaction of the azaallyllithiums derived from imines of α-amino esters with benzynes results in the formation of 1,3-dihydroisoindoles and 4-hydroxyisoquinolines via 3+2 and 2+2 cycloadditions, respectively. The initially formed 1-carboethoxy-1,3-dihydroisoindoles rearrange under basic reaction conditions to form 3-(2H)-isoquinolinones.