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Fluorescent detection of chemical warfare agents: Functional group specific ratiometric chemosensors
Zhang, Shi-Wei,Swager, Timothy M.
, p. 3420 - 3421 (2007/10/03)
Indicators providing highly sensitive and functional group specific fluorescent response to diisopropyl fluorophosphate (DFP, a nerve gas (G-agent) simulant) are reported. Nonemissive indicator 2 reacts with DFP to give a cyclized compound 2+A- that shows a high emission due to its highly planar and rigid structure. Very weak emission was observed by the addition of HCl. Another indicator based on pyridyl naphthalene exhibits a large shift in its emission spectrum after reaction with DFP, which provides for quantitative ratiometric detection. Copyright
