517892-64-7Relevant academic research and scientific papers
Novel enantioselective receptors for N-protected glutamate and aspartate
Ragusa, Andrea,Rossi, Sara,Hayes, Joseph M.,Stein, Matthias,Kilburn, Jeremy D.
, p. 5674 - 5688 (2007/10/03)
A series of chiral bisthiourea macrocycles 1-4 have been prepared and their binding properties with various dicarboxylate salts have been examined by using NMR titration and isothermal calorimetry experiments. Macrocycle 1, in particular, favours the 1:1
A highly enantioselective receptor for N-protected glutamate and anomalous solvent-dependent binding properties
Rossi, Sara,Kyne, Graham M.,Turner, David L.,Wells, Neil J.,Kilburn, Jeremy D.
, p. 4233 - 4236 (2007/10/03)
Solvation of the macrocycle by polar solvents leads to strong binding of an N-protected excitatory amino acid neurotransmitter. A 1:1 complex forms highly enantioselectively between the macrocycle and N-Boc-L-glutamate (as the dicarboxylate anion, see pic
