517904-33-5Relevant articles and documents
Synthesis of linear and cyclic dimeric ester derivatives from bile acids and glycine
Tian, Ze,Cui, Hong,Wang, Yan
, p. 3821 - 3829 (2002)
Two novel taylor-made linear and cyclic dimers were synthesized from the inexpensive steroid bile acids and amino acid glycine. The structures and stereochemistry of all intermediates and dimers were determined by means of spectroscopic analyses.
Chemical modifications of bile acids under high-intensity ultrasound or microwave irradiation
Cravotto, Giancarlo,Boffa, Luisa,Turello, Marta,Parenti, Massimo,Barge, Alessandro
, p. 77 - 83 (2007/10/03)
High-intensity ultrasound (HIU) and microwave (MW) irradiation, having emerged as effective promoters of organic reactions, were exploited for the synthesis of bile acids derivatives. Esterification, amidation, hydrolysis, oxidation, and reduction were investigated. Compared to conventional methods, both techniques proved much more efficient, increasing product yields and dramatically cutting down reaction times. Scaled-up studies are now under way.
