51799-32-7 Usage
Uses
Used in Pharmaceutical Industry:
d-N-propylamphetamine is used as a research chemical for the development of treatments for neurological disorders, primarily due to its effects on neurotransmitter levels.
Used in Neurological Treatments:
d-N-propylamphetamine is used as a potential therapeutic agent for conditions such as attention-deficit/hyperactivity disorder (ADHD) and narcolepsy, leveraging its stimulant properties to address the symptoms of these disorders.
Used in Controlled Substances Regulation:
d-N-propylamphetamine is used as a subject of regulatory control to mitigate the risks of abuse and addiction associated with its psychoactive effects, ensuring that its distribution and use are monitored and restricted to prevent recreational misuse.
Check Digit Verification of cas no
The CAS Registry Mumber 51799-32-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,7,9 and 9 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 51799-32:
(7*5)+(6*1)+(5*7)+(4*9)+(3*9)+(2*3)+(1*2)=147
147 % 10 = 7
So 51799-32-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H19N/c1-3-9-13-11(2)10-12-7-5-4-6-8-12/h4-8,11,13H,3,9-10H2,1-2H3
51799-32-7Relevant academic research and scientific papers
Quantitative structure-activity relationships in drug metabolism and disposition: Pharmacokinetics of N-substituted amphetamines in humans
Testa,Salvesen
, p. 497 - 501 (2007/10/02)
Pharmacokinetic data of 15 N-alkyl-substituted amphetamines in humans have been the object of a retrospective quantitative structure-activity relationship study. The urinary excretion of amphetamines was shown to decrease with increasing lipophilicity; the correlation equations revealed that, for identical lipophilicities, tertiary amines are excreted faster than secondary amines, which are secreted faster than primary amines. The apparent n-heptane-pH 7.4 buffer partition coefficient correlates better with urinary excretion than does the true n-octanol-water partition coefficient, probably because it includes a pKa term that accounts for the fraction of the drug present in the tubules as nonionic species. The N-dealkylation rate increases with increasing lipophilicity of the substrates (enhanced enzyme affinity) but decreases with increasing bulk of the N-substituent that is split off (steric hindrance of initial C(α)-hydroxylation.
