518028-23-4

Basic information

• Product Name: 2-Fluoro-9-(2,3,5-tri-O-benzoyl-α-L-lyxofuranosyl)-9H-purin-6-amine
• Synonyms: 2-Fluoro-9-(2,3,5-tri-O-benzoyl-α-L-lyxofuranosyl)-9H-purin-6-amine
• CAS NO: 518028-23-4
• Molecular Weight: 597.559
• Mol File: 518028-23-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Fluoro-9-(2,3,5-tri-O-benzoyl-α-L-lyxofuranosyl)-9H-purin-6-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluoro-9-(2,3,5-tri-O-benzoyl-α-L-lyxofuranosyl)-9H-purin-6-amine(518028-23-4)
• EPA Substance Registry System: 2-Fluoro-9-(2,3,5-tri-O-benzoyl-α-L-lyxofuranosyl)-9H-purin-6-amine(518028-23-4)

Safety Data

• Hazardous Substances Data: 518028-23-4(Hazardous Substances Data)

Upstream product

• 700-49-2 2-fluoroadenine 
• 22249-17-8 1-O-acetyl-2,3,5-tri-O-benzoyl-L-lyxofuranose 

Relevant articles and documents

Synthesis and biological activity of 2-fluoro adenine and 6-methyl purine nucleoside analogs as prodrugs for suicide gene therapy of cancer

A novel series of 6-methylpurine nucleoside derivatives with substitutions at 5′-position have been synthesised. These compounds bear a 5′-heterocycle such as triazole or a imidazole with a two carbon chain, and an ether, thio ether or amine. To extend the SAR study of 2-fluoroadenine and 6-methyl purine nucleosides, their corresponding α-linker nucleosides with L-xylose and L-lyxose were also synthesized. All of these compounds have been evaluated for their substrate activity with E. coli PNP. Copyright Taylor & Francis, Inc.