518051-96-2 Usage
General Description
2,3,4,5-tetrahydro-1H-benzo[b]azepin-8-amine, also known as tetrabenazine, is a chemical compound with pharmaceutical properties. It is primarily used as a monoamine-depleting agent and functions as a reversible inhibitor of vesicular monoamine transporter 2 (VMAT2). Tetrabenazine is primarily used for the treatment of hyperkinetic movement disorders, such as Huntington's disease and tardive dyskinesia. It works by reducing the levels of dopamine and other monoamines in the brain, helping to control abnormal movements and muscle contractions associated with these conditions. However, it may also produce side effects, including sedation, depression, and parkinsonism.
Check Digit Verification of cas no
The CAS Registry Mumber 518051-96-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,1,8,0,5 and 1 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 518051-96:
(8*5)+(7*1)+(6*8)+(5*0)+(4*5)+(3*1)+(2*9)+(1*6)=142
142 % 10 = 2
So 518051-96-2 is a valid CAS Registry Number.
518051-96-2Relevant articles and documents
Synthesis and biological evaluation of benzazepine oxazolidinone antibacterials
Johnson, Paul D.,Aristoff, Paul A.,Zurenko, Gary E.,Schaadt, Ronda D.,Yagi, Betty H.,Ford, Charles W.,Hamel, Judith C.,Stapert, Douglas,Moerman, Judy K.
, p. 4197 - 4200 (2007/10/03)
Novel benzazepine oxazolidinone antibacterials were synthesized and evaluated against clinically relevant susceptible and resistant organisms. The effect of ring nitrogen position and N-substitution on antibacterial activity is examined.
