518061-69-3

Basic information

• Product Name: N-benzyl-4-phenyl-3-butynamide
• Synonyms: N-benzyl-4-phenyl-3-butynamide
• CAS NO: 518061-69-3
• Molecular Weight: 249.312
• Mol File: 518061-69-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-benzyl-4-phenyl-3-butynamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-4-phenyl-3-butynamide(518061-69-3)
• EPA Substance Registry System: N-benzyl-4-phenyl-3-butynamide(518061-69-3)

Safety Data

• Hazardous Substances Data: 518061-69-3(Hazardous Substances Data)

Upstream product

• 64297-96-7 N-(iodoacetyl)benzylamine 
• 536-74-3 phenylacetylene 
• 2564-06-9 N-benzyl-2-chloroacetamide 
• 2945-03-1 N-benzyl-2-bromoacetamide 
• 3757-88-8 tributylstannylethynylbenzene 

Relevant articles and documents

Triethylborane-induced radical reaction of alkynylgallium with α-halo carbonyl compounds

Treatment of terminal acetylenes with butyllithium, followed by an addition of gallium trichloride, afforded the corresponding alkynylgallium reagents. The reaction of the resulting alkynylgallium with α-halo carbonyl compounds in the presence of triethylborane as a radical initiator provided β,γ-acetylenic carbonyl compounds in good yields.

Alkynylation of α-halocarbonyl compounds - A Stille-type cross-coupling for the formation of C(sp)-C(sp3) bonds under neutral conditions

A direct alkynylation of readily available α-halo esters and amides with high yields is described herein; a distinct switch from diyne formation to alkynylation products was attained under neutral conditions. The Royal Society of Chemistry.