518062-89-0Relevant academic research and scientific papers
6-Chloro-2(2H)-pyranone: A new 2(2H)-pyranone synthon
Biagetti, Matteo,Bellina, Fabio,Carpita, Adriano,Rossi, Renzo
, p. 607 - 610 (2007/10/03)
6-Chloro-2(2H)-pyranone, which can be prepared in high yield from commercially available trans-glutaconic acid, undergoes facile Pd/Cu-catalyzed reaction with various 1-alkynes to give rise to the corresponding 6-(1-alkynyl)-2(2H)-pyranones in moderate to good yields. These last hitherto unknown compounds have been used as direct precursors to 6-alkyl- and 6-[(Z)-1-alkenyl]-2(2H)-pyranones.
