51808-10-7

Usage

Uses

Used in Organic Synthesis:
(1-phenyl-1H-1,2,3-triazole-4,5-diyl)dimethanol serves as a versatile building block in the synthesis of a wide range of organic compounds, leveraging its reactive functional groups and structural features.
Used in Pharmaceutical and Medicinal Chemistry:
(1-phenyl-1H-1,2,3-triazole-4,5-diyl)dimethanol is utilized as a ligand in coordination chemistry, contributing to the development of novel pharmaceutical agents. Its triazole ring is known for exhibiting diverse biological activities, positioning it as a promising candidate for drug development.
Used in Materials Science:
(1-phenyl-1H-1,2,3-triazole-4,5-diyl)dimethanol's unique structure and properties make it a valuable component in the advancement of new materials with specific properties for various applications.

Upstream product

• 110-65-6 1,4-dihydroxybut-2-yne 
• 622-37-7 Phenyl azide 
• 17304-69-7 1-phenyl-1H-[1,2,3]triazole-4,5-dicarboxylic acid dimethyl ester 

Downstream Products

• 92126-29-9 1-phenyl-4,5-bis(hydroxymethyl)-1,2,3-triazole bis(methylcarbamate) 
• 129748-83-0 Isopropyl-carbamic acid 5-isopropylcarbamoyloxymethyl-3-phenyl-3H-[1,2,3]triazol-4-ylmethyl ester 
• 143850-00-4 4,5-bis(bromomethyl)-1-phenyl-1,2,3-triazole 
• 143850-01-5 4,5-dihydro-4,5-dimethylene-1-phenyl-1,2,3-triazole 
• 143850-03-7 1-Phenyl-4,7-dihydro-1H-[1,2,3]triazolo[4,5-d]pyridazine-5,6-dicarboxylic acid diethyl ester 
• 143850-02-6 6-Methyl-1-phenyl-4,4a,7a,8-tetrahydro-1H-pyrrolo[3',4':4,5]benzo[1,2-d][1,2,3]triazole-5,7-dione 
• 22758-02-7 1-phenyl-1H-[1,2,3]triazole-4,5-dicarboxylic acid 

Relevant academic research and scientific papers

Synthesis of 1-aryl(hetaryl)-1,2,3-triazoles with the use of ionic liquids

1-Phenyl(furazanyl)-1,2,3-triazoles can be synthesised by the 1,3-dipolar cycloaddition of phenylazide 1 or 4-amino-3-azido-furazan 2 to acetylenes (or to 1-morpholinyl-2-nitroethene for 2) in ionic liquids { 1-butyl-3-methylimidazolium tetrafluoroborate

Generation and cycloaddition reactions of the 1,2,3-triazole analogue of o-quinodimethane

4,5-Dihydro-4,5-dimethylene-1-phenyl-1,2,3-triazole (4), the 1,2,3-triazole analogue ofσ-quinodimethane, can be generated in situ from 4,5-bis(bromomethyl) derivative (3) by sodium iodide induced 1,4-elimination process. By trapping the 1,4-dimethylene-tr

Synthesis and evaluation of furan, thiophene, and azole bis[(carbamoyloxy)methyl] derivatives as potential antineoplastic agents

A series of bis(hydroxymethyl)-substituted heterocycles were synthesized and converted to the corresponding bis(methylcarbamate) derivatives. The heterocyclic systems studied were based on 2-phenyl-3-methylfuran, 1-phenylpyrazole, 1-phenyl-5-methylpyrazole, 1-phenyl-5-methylthiopene, 1-phenyl-1,2,3-triazole, 3-phenylisoxazole, 3-phenylisothiazole, 2-phenylthiazole, and 2-phenyloxazole. None of the bis(carbamates) prepared was active against murine P388 lymphocytic leukemia. Pyrrole bis(carbamate), which exhibited antileukemic activity, also showed reactivity toward 4-(p-nitrobenzyl)pyridine while the inactive bis(carbamates) were unreactive in the 4-(p-nitrobenzyl)pyridine assay.