5181-05-5

Usage

Uses

Used in Pharmaceutical Production:
2-aminopropanedinitrile is utilized as an intermediate in the synthesis of various pharmaceuticals. Its chemical properties make it a valuable component in the development of new drugs and medications.
Used in Agrochemical Production:
2-aminopropanedinitrile also serves as an intermediate in the production of agrochemicals, contributing to the development of products used in agriculture to protect crops and enhance yields.
Used in Organic Compound Synthesis:
2-aminopropanedinitrile is employed in the synthesis of other organic compounds, broadening its applications across different industries that rely on organic chemistry.
Used as a Monomer in Polymer Production:
In the field of polymer chemistry, 2-aminopropanedinitrile is used as a monomer for the production of polymers such as nylon and polyamides, which are used in a wide range of applications from textiles to engineering materials.

InChI:InChI=1/C3H3N3/c4-1-3(6)2-5/h3H,6H2

Upstream product

• 1885-22-9 bromomalononitrile 
• 62009-47-6 2-aminopropanediamide 
• 109-77-3 malononitrile 

Downstream Products

• 5098-16-8 5-amino-2-methyl-1,3-oxazole-4-carbonitrile 
• 5098-17-9 2-ethyl-5-amino-4-cyano-1,3-oxazole 
• 5098-18-0 5-amino-2-phenyl[1,3]oxazole-4-carbonitrile 
• 412943-69-2 5-amino-1-phenethylimidazole-4-carbonitrile 
• 5098-11-3 4-amino-1H-imidazole-5-carbonitrile 
• 27700-57-8 5-amino-1-cyclohexylimidazole-4-carbonitrile 

Relevant academic research and scientific papers

Synthetic method of 2-aminomalononitrile

The invention discloses a synthetic method of 2-aminomalononitrile. The synthetic method comprises the following steps of: 1) adopting aminomalonic acid diethyl ester as a starting material, directlyplacing into 40-60w/v% of ammonium-chloride aqueous solution, reacting for 2-5 hours at a temperature of 100-120 DEG C and preparing to obtain 2-aminopropanediamide; 2) dissolving 2-aminopropanediamide prepared in the step 1) into an organic solvent, heating to rise the temperature, adding solid phosgene, heating and refluxing for 10-12 hours to generate 2-aminomalononitrile. The synthetic methoddisclosed by the invention is simple, pollution-free, safe and environmentally friendly and provides basis for further application of 2-aminomalononitrile.

Process for the production of aminomalonic acid dinitrile as an aminomalonic acid dinitriltosylate precipitate or as an acetylaminomalodinitrile precipitate

Process for the production of aminomalonic acid dinitrile from a malonic acid dinitrile compound, such as oximinomalonic acid dinitrile or phenylazomalonic acid dinitrile. The reaction is carried out at an elevated hydrogen pressure in the presence of Raney catalysts and a solvent. When tetrahydrofurane is used as a solvent, the reaction product is precipitated with p-toluene sulfonic acid. When acetic anhydride is used as solvent, the reaction product is precipitated as acetyl aminomalonic acid dinitrile.

Purines, Pyrimidines, and Imidazoles. Part 56. Some Aminoimidazolecarboxamidines and Derived Adenines

5-Amino-4-cyano-1-cyclohexylimidazole, prepared from aminomalononitrile, triethyl orthoformate, and cyclohexylamine with methanolic hydrogen chloride, produced methyl 5-amino-1-cyclohexylimidazole-4-carboximidate, which with ammonia gave 5-amino-1-cyclohe