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1,4-di-tert-butyl-2-iodobenzene is an organic compound with the chemical formula C14H21I. It is a derivative of benzene, featuring two tert-butyl groups (C4H9) attached to the 1st and 4th carbon atoms, and an iodine atom (I) at the 2nd carbon position. This molecule is characterized by its symmetrical structure and the presence of a halogen atom, which can participate in various chemical reactions. It is often used as a precursor in the synthesis of other organic compounds, particularly in the pharmaceutical and chemical industries. Due to its stability and reactivity, 1,4-di-tert-butyl-2-iodobenzene is a valuable intermediate in the preparation of various functionalized aromatic compounds.

5182-66-1

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5182-66-1 Usage

Structure

Substituted benzene ring with two tert-butyl groups and an iodine atom attached to the 1 and 4 positions, respectively.

Applications

a. Organic synthesis
b. Building block for complex organic molecules
c. Starting material for pharmaceuticals, agrochemicals, and materials science applications

Steric hindrance

Increased by the presence of tert-butyl groups, making it useful for selective alkylation reactions.

Reactivity

a. Iodine atom as a leaving group in substitution reactions
b. Versatile in a wide range of synthetic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 5182-66-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,8 and 2 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5182-66:
(6*5)+(5*1)+(4*8)+(3*2)+(2*6)+(1*6)=91
91 % 10 = 1
So 5182-66-1 is a valid CAS Registry Number.

5182-66-1Upstream product

5182-66-1Relevant academic research and scientific papers

Synthesis and gas permeation properties of poly(diarylacetylene)s having substituted and twisted biphenyl moieties

Hu, Yanming,Shimizu, Toshiyuki,Hattori, Kyohei,Shiotsuki, Masashi,Sanda, Fumio,Masuda, Toshio

scheme or table, p. 861 - 868 (2010/11/05)

Diarylacetylene monomers containing substituted biphenyl (1a-f) and anthryl (1g) groups were synthesized and then polymerized with TaCl5-n- Bu4Sn catalyst to produce the corresponding poly(diarylacetylene)s (2a-g). Polymers 2a-f were

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