518335-32-5

Basic information

• Product Name: tert-butyl (R)-1-(naphthalen-1-yl)ethylcarbamate
• Synonyms: tert-butyl (R)-1-(naphthalen-1-yl)ethylcarbamate
• CAS NO: 518335-32-5
• Molecular Weight: 271.359
• Mol File: 518335-32-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: tert-butyl (R)-1-(naphthalen-1-yl)ethylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (R)-1-(naphthalen-1-yl)ethylcarbamate(518335-32-5)
• EPA Substance Registry System: tert-butyl (R)-1-(naphthalen-1-yl)ethylcarbamate(518335-32-5)

Safety Data

• Hazardous Substances Data: 518335-32-5(Hazardous Substances Data)

Usage

General Description

Tert-butyl (R)-1-(naphthalen-1-yl)ethylcarbamate, also known as bioallethrin, is a synthetic pyrethroid insecticide typically used in household insecticide products such as sprays, coils, and vaporizers. It is highly effective against a wide range of household pests, including mosquitoes, flies, cockroaches, and ants, and is known for its quick knockdown and long-lasting residual effects. However, it is also toxic to aquatic organisms and can be harmful to humans and pets if ingested or inhaled in large quantities. Overall, while tert-butyl (R)-1-(naphthalen-1-yl)ethylcarbamate is effective in controlling household pests, it should be used with caution and in accordance with safety guidelines to minimize potential risks to humans and the environment.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 3886-70-2 (R)-1-(1-Naphthyl)ethylamine 

Downstream Products

• 1355993-08-6 (R)-tert-butyl-3-(3-chlorophenyl)propyl(1-(naphthalen-1-yl)-ethyl)carbamate 
• 1204313-91-6 (R)-tert-butyl (1-(naphthalen-1-yl)ethyl)(3-(3-(trifluoromethyl)phenyl)propyl)carbamate 
• 364782-34-3 cinacalcet hydrochloride 

Relevant articles and documents

Cinacalcet intermediate and synthesis method of cinacalcet hydrochloride

The invention relates to a cinacalcet intermediate and a synthesis method of cinacalcet hydrochloride. The synthesis method of cinacalcet hydrochloride comprises the steps of (c) in an organic solvent, carrying out olefin metathesis reaction on a compound N-III and a compound B-2 under the action of a catalyst to obtain a compound C-I; (d) carrying out hydrogenation reduction reaction on the compound C-I to obtain a compound C-II; and (e) removing an amino protecting group from the compound C-II, and salifying with hydrogen chloride to obtain cinacalcet hydrochloride. The method has the advantages of high yield, high chemical purity and optical purity of the product, simple post-treatment process, simple and easily available raw materials, and facilitation of industrial production. The reaction formula is shown in the description, wherein R is selected from t-butyloxycarbonyl, benzoyl and carbobenzoxy.

PROCESS FOR PREPARING CINACALCET AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF

The resent invention rovides a novel rocess for re arin cinacalcet of formula I and pharmaceutically acceptable salts thereof and process of purification. The present invention also provides novel nitrogen protected synthetic intermediates useful in the process of the present invention. Further, the present invention provides a novel substituted carbamate impurity and process of preparation thereof.