518336-20-4 Usage
General Description
4-(1-Hydroxyethyl)phenylboronic acid is a chemical compound with the formula C8H11BO3. It is a boronic acid derivative and contains a phenyl group attached to a boronic acid functional group along with a hydroxyethyl substituent. 4-(1-Hydroxyethyl)phenylboronic acid is commonly used in organic synthesis and medicinal chemistry as a reagent for the Suzuki coupling reaction to form carbon-carbon bonds. Its boronic acid group allows it to selectively bind to diols and other Lewis bases, making it useful for the detection and extraction of specific molecules in biological and environmental samples. Additionally, 4-(1-Hydroxyethyl)phenylboronic acid has been studied for its potential use in drug delivery systems and in the development of materials with functional properties.
Check Digit Verification of cas no
The CAS Registry Mumber 518336-20-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,1,8,3,3 and 6 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 518336-20:
(8*5)+(7*1)+(6*8)+(5*3)+(4*3)+(3*6)+(2*2)+(1*0)=144
144 % 10 = 4
So 518336-20-4 is a valid CAS Registry Number.
InChI:InChI=1S/C8H11BO3/c1-6(10)7-2-4-8(5-3-7)9(11)12/h2-6,10-12H,1H3
518336-20-4Relevant articles and documents
Multistep phase-switch synthesis by using liquid-liquid partitioning of boronic acids: Productive tags with an expanded repertoire of compatible reactions
Mothana, Sam,Grassot, Jean-Marie,Hall, Dennis G.
supporting information; experimental part, p. 2883 - 2887 (2010/07/06)
(Figure Presented) Tagging along: A system for phase-switch synthesis has been developed. The boronic acid functionality is used as a phase tag that complexes to sorbitol and facilitates compound transfer from an organic solvent to water at high pH. The phase tag can then be used in a productive reaction step to generate targeted products, thereby eliminating purification by silica gel chromatography.
Oxidation of hydroxyl-substituted organotrifluoroborates
Molander, Gary A.,Petrillo, Daniel E.
, p. 9634 - 9635 (2007/10/03)
Potassium- and tetra-n-butylammonium organotrifluoroborates containing hydroxyl groups have been prepared and oxidized using several common oxidants. Aryl-, alkenyl-, and alkyltrifluoroborates containing both primary and secondary hydroxyl groups were oxi
