Cas 518346-75-3,C22H26N2O4

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Check Digit Verification of cas no

The CAS Registry Mumber 518346-75-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,1,8,3,4 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 518346-75:
(8*5)+(7*1)+(6*8)+(5*3)+(4*4)+(3*6)+(2*7)+(1*5)=163
163 % 10 = 3
So 518346-75-3 is a valid CAS Registry Number.

518346-75-3Upstream product

1000771-23-2 C₂₃H₂₈N₂O₄

518346-75-3Downstream Products

518346-75-3Relevant academic research and scientific papers

Synthesis and evaluation of novel pyrazolidinone analogs of PGE2 as EP2 and EP4 receptors agonists

Zhao, Zhong,Araldi, Gian Luca,Xiao, Yufang,Reddy, Adulla P.,Liao, Yihua,Karra, Srinivasa,Brugger, Nadia,Fischer, David,Palmer, Elizabeth

, p. 6572 - 6575 (2008/09/16)

Replacement of the hydroxy cyclopentanone ring in PGE2 with chemically more stable heterocyclic rings and substitution of the unsaturated α-alkenyl chain with a metabolically more stable phenethyl chain led to the development of potent and selective analogs of PGE2. Compound 10f showed the highest potency and selectivity for EP4 the receptor.

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