5184-75-8

Usage

InChI:InChI=1/C16H18O2S/c1-11-5-7-15(13(3)9-11)19(17,18)16-8-6-12(2)10-14(16)4/h5-10H,1-4H3

Upstream product

• 88-61-9 2,4-dimethylbenzenesulfonic acid 
• 108-38-3 m-xylene 
• 96-77-5 4-hydroxy-benzene-1,3-disulfonic acid 
• 88-42-6 2,5-dichlorobenzenesulfonic acid 
• 609-60-9 2,4-dimethylbenzenesulfonyl chloride 
• 201230-82-2 carbon monoxide 
• 7790-94-5 chlorosulfonic acid 
• 106-42-3 para-xylene 

Relevant academic research and scientific papers

Facile synthesis of diarylsulfones from arenes and 3CdSO4·xH2O via mechanochemistry

A variety of substituted diarylsulfones could be synthesized by simple arenes and 3CdSO4·xH2O in the presence of P2O5 under high-speed ball milling. It was suggest the aromatic sulfonation was performed by arene and in situ generated H2SO4, following-up by electrophilic substitution with another arene to give diarylsulfone.

The synthesis of diarylsulfones with simple arenes and K2S2O8 through double C-S bond formation

An unprecedented double C-S bond formation method has been developed to prepare both symmetric and unsymmetric diarylsulfones with simple arenes in a single step. This represents the first example that K2S2O8 can be employed as a highly effective sulfonating agent to synthesize diarylsulfones. The reaction demonstrates excellent reactivity, good functional group tolerance and high yields.

Synthesis of symmetric diaryl sulfones with dimethyl sulfate

In this procedure dimethyl sulfate was used for preparation of symmetric diaryl sulfones. First, dimethyl sulfate was treated with pyridine, then activated by Tf2O to generate SO2 as the functional group for synthesis of diaryl sulfones. It is noticeable that this reaction was carried out in moderate conditions and products obtained in short times and good yields.

Formylation of Aromatic Compounds with CO in HSO3F-SbF5 under Atmospheric Pressure

The formylation of aromatic compounds such as benzene, toluene, xylenes, mesitylene, indan, tetralin, fluorobenzene, chlorobenzene, and bromobenzene was carried out in HSO3F-SbF5 under atmospheric CO pressure at 0 deg C.In HSO3F-SbF5, both formylation and sulfonation took place to give formyl and sulfonyl compounds.In the case of alkylbenzenes, including toluene, xylenes, mesitylene, and tetralin, formylalkylbenzenesulfonyl fluorides, new compounds, were obtained by a one-pot reaction as well as alkylbenzaldehydes, alkylbenzenesulfonyl fluorides, and bis(alkylphenyl) sulfones.The direct introduction of a formyl and sulfonyl group was achieved in alkylbenzenes.The reaction path of the new compounds is a two-step reaction comprised of formylation as the first step and sulfonation as the second step.The product composition was strongly dependent on the acid strength of the HSO3F-SbF5 systems.The formyl compounds became predominant with increasing acidity of the HSO3F-SbF5 system.On the other hand, only sulfonyl compounds were produced when the acidity of the HSO3F-SbF5 system was low.

Novel Sulfonylation reagent: Sulfuric Acid-Hexafluoroacetic Anhydride

A mixture of sulfuric acid and hexafluoroacetic anhydride is an efficient reagent for the sulfonylation of aromatic compounds.