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(S)-N-(2,6-dioxo-1-phenethylpiperidin-3-yl)isobutyramide is a complex organic compound with the molecular formula C18H22N2O4. It is a chiral molecule, with the "S" prefix indicating that it has the (S)-configuration, meaning the substituents are arranged in a specific three-dimensional orientation. (S)-N-(2,6-dioxo-1-phenethylpiperidin-3-yl)isobutyramide is characterized by a piperidine ring, which is a six-membered nitrogen-containing ring, and an isobutyramide group, which is an amide derived from isobutyric acid. The 2,6-dioxo-1-phenethyl group attached to the piperidine ring suggests the presence of two oxygen atoms at the 2 and 6 positions, and a phenethyl side chain connected to the nitrogen atom. This chemical structure is significant in medicinal chemistry, as it can influence the compound's biological activity and pharmacological properties. The specific arrangement of atoms and functional groups in (S)-N-(2,6-dioxo-1-phenethylpiperidin-3-yl)isobutyramide can affect its interactions with biological targets, making it a potential candidate for drug development or as a chemical intermediate in the synthesis of other pharmaceuticals.

51870-97-4

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51870-97-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 51870-97-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,8,7 and 0 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 51870-97:
(7*5)+(6*1)+(5*8)+(4*7)+(3*0)+(2*9)+(1*7)=134
134 % 10 = 4
So 51870-97-4 is a valid CAS Registry Number.

51870-97-4Downstream Products

51870-97-4Relevant academic research and scientific papers

Glutarimide Alkaloids Through Multicomponent Reaction Chemistry

Konstantinidou, Markella,Kurpiewska, Katarzyna,Kalinowska-T?uscik, Justyna,D?mling, Alexander

, p. 6714 - 6719 (2018/11/25)

A concise four step synthetic route for glutarimide alkaloids of high biological interest is presented. The scaffold is accessed via an Ugi four component reaction, hereby introducing two points of variation. This is followed by a hydrolysis, a cyclization under mild conditions, and an amine deprotection. The diastereomers of the cyclized intermediate can be easily separated, thus leading to optically pure alkaloids. By this route, four natural products and ten derivatives were synthesized. The scope and limitations of the synthetic methodology were investigated.

Enantioselective synthesis of glutarimide alkaloids cordiarimides A, B, crotonimides A, B, and julocrotine

Teng, Bo,Zheng, Jianfeng,Huang, Huiying,Huang, Peiqiang

, p. 1312 - 1318 (2011/10/31)

Five glutarimide alkaloids cordiarimide A (5), cordiarimide B (6), crotonimide A (3), crotonimide B (4), and julocrotine (2) have been synthesized starting from Boc-L-glutamine (7). The benzylic alcohol chiral centre of cordiarimides B (6) has been established in 6:1 diastereoselectivity by catalytic asymmetric hydrogenation using Zhou's catalytic system Pd(CF 3CO2)2/(R,R)-Me-DuPhos. Copyright

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