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LY-573636 is a potent, selective, and orally bioavailable inhibitor of Raf kinase, a key enzyme in the MAPK/ERK signaling pathway, which plays a crucial role in cell proliferation, differentiation, and survival. Its ability to effectively inhibit the growth of various human tumor cell lines, including those resistant to other Raf inhibitors, makes it a promising anti-tumor agent with potential applications in cancer therapeutics.

519055-63-1

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519055-63-1 Usage

Uses

Used in Oncology:
LY-573636 is used as an anti-tumor agent for its significant antitumor activity in preclinical studies. It has demonstrated the ability to inhibit the growth of various human tumor cell lines and induce tumor regression in mouse xenograft models. Its selectivity for Raf kinase and favorable pharmacokinetic and safety profiles make it a potential candidate for the development of novel cancer therapeutics.
Used in Drug Resistance:
LY-573636 is used as a therapeutic agent for overcoming drug resistance in cancer treatment. Its effectiveness against tumor cell lines resistant to other Raf inhibitors highlights its potential to address the challenge of drug resistance in cancer therapy.
Used in Cancer Research:
LY-573636 is used as a research tool for studying the role of Raf kinase in cancer development and progression. Its potent and selective inhibition of Raf kinase allows researchers to investigate the molecular mechanisms underlying the anti-tumor activity of LY-573636 and identify potential therapeutic targets for cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 519055-63-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,1,9,0,5 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 519055-63:
(8*5)+(7*1)+(6*9)+(5*0)+(4*5)+(3*5)+(2*6)+(1*3)=151
151 % 10 = 1
So 519055-63-1 is a valid CAS Registry Number.

519055-63-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name sodium,(5-bromothiophen-2-yl)sulfonyl-(2,4-dichlorobenzoyl)azanide

1.2 Other means of identification

Product number -
Other names Tasisulam sodium

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:519055-63-1 SDS

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