51909-10-5Relevant academic research and scientific papers
Base-Promoted Oxidative Dearomatization of Pyrroles to 4-Pyrrolin-2-ones
Huang, Huabin,Hu, Bing,Lai, Yuanfa,Zou, Zhongai,Lin, Huixia,Xiao, Yujuan,You, Qihua,Shen, Jinhai
, p. 3906 - 3910 (2018)
A base-promoted oxidative dearomatization of substituted pyrroles for the synthesis of 3,3-disubstituted 4-pyrrolin-2-ones under mild reaction conditions is described. A cascade aerobic oxidation/semipinacol rearrangement reaction was involved, and the desired products bearing a quaternary carbon center were efficiently prepared using molecular oxygen (O2) as an ideal oxidant. (Figure presented.).
