51953-07-2Relevant academic research and scientific papers
Free-radical anti-Markovnikov hydroalkylation of unactivated alkenes with simple alkanes
Tian, Yunfei,Ling, Anbo,Fang, Ren,Tan, Ren Xiang,Liu, Zhong-Quan
supporting information, p. 3432 - 3435 (2018/08/07)
A Cu(ii)-mediated radical anti-Markovnikov hydroalkylation of unactivated alkenes with simple alkanes via selective C(sp3)-H bond cleavage was achieved. This reaction features high site-selectivity diverse functional group tolerance, and scalability.
Compositions and methods for inhibiting pain
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Sheet 3, (2008/06/13)
A method and pharmaceutical composition for ameliorating pain in a human or non-human mammal suffering therefrom based on an antinociceptive amine having the formula: wherein: Z is H or OH, is phenyl or cyclohexyl, R and R1 are the same or diff
COMPOSITIONS AND METHODS FOR INHIBITING PAIN
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Page/Page column 10, 3/10, (2008/06/13)
A method and pharmaceutical composition for ameliorating pain in a human or non-human mammal suffering therefrom based on an antinociceptive amine having the formula: (I) wherein: Z is H or OH, (II) is phenyl or cyclohexyl, R and Rl are the sam
IMIDAZO[4,5-B]PYRIDINE DERIVATIVES AS CARDIOVASCULAR AGENTS
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, (2008/06/13)
Disclosed are the compounds of the formula STR1 wherein R represents hydrogen, lower alkyl, aryl or aryl-lower alkyl; R 1 represents hydrogen, lower alkyl, C 3-C 7-alkenyl, carbocyclic or heterocyclic aryl, carbocyclic or heterocyclic aryl-lower alkyl, C 3-C 7-cycloalkyl, or optionally lower alkyl substituted (C 3-C. sub.7-cycloalkyl, bicycloheptyl, bicycloheptenyl, adamantyl, tetrahydropyranyl or tetrahydrothiopyranyl)-lower alkyl, or diaryl-lower alkyl; R 2 represents hydrogen or lower alkyl; R 3 represents hydroxymethyl or--CONHR 4 in which R 4 represents hydrogen, lower alkyl, aryl-lower alkyl, C 3-C 7-cycloalkyl, C 3-C. sub.7-cycloalkyl-lower alkyl or hydroxy-lower alkyl; pharmaceutically acceptable ester derivatives thereof in which one or more of the hydroxy groups are esterified in form of a pharmaceutically acceptable ester; and pharmaceutically acceptable salts thereof; methods of preparation; pharmaceutical compositions; and their use as adenosine-2 agonists in mammals.
