51982-36-6 Usage
Uses
Used in Pharmaceutical Applications:
Prostaglandin G2 is used as a therapeutic agent for its potential role in modulating immune responses and influencing tumor biology. Its ability to inhibit indoleamine 2,3-dioxygenase activity makes it a promising candidate for the development of treatments targeting immune suppression and tumor-induced tolerance.
Used in Research and Development:
In the field of biomedical research, Prostaglandin G2 is used as a key intermediate in the COX pathway for studying the mechanisms underlying inflammation, pain, and other related conditions. Understanding the role of PGG2 in these processes can lead to the development of novel drugs and therapies for various diseases.
Used in Drug Delivery Systems:
Similar to gallotannin, Prostaglandin G2 can also be incorporated into drug delivery systems to enhance its bioavailability, delivery, and therapeutic outcomes. These systems can be tailored to improve the efficacy of PGG2 in modulating immune responses and targeting tumor biology, potentially leading to more effective treatments for various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 51982-36-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,9,8 and 2 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 51982-36:
(7*5)+(6*1)+(5*9)+(4*8)+(3*2)+(2*3)+(1*6)=136
136 % 10 = 6
So 51982-36-6 is a valid CAS Registry Number.
InChI:InChI=1/C20H32O6/c1-2-3-6-9-15(24-23)12-13-17-16(18-14-19(17)26-25-18)10-7-4-5-8-11-20(21)22/h4,7,12-13,15-19,23H,2-3,5-6,8-11,14H2,1H3,(H,21,22)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1
51982-36-6Relevant academic research and scientific papers
COX-2-targeted imaging agents
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Page/Page column 6, (2008/06/13)
The presently disclosed subject matter provides a method for synthesizing a radiological imaging agent by reacting a COX-2-selective ligand with a compound comprising a detectable group, wherein the COX-2-selective ligand is a derivative of a non-steroidal anti-inflammatory drug (NSAID) comprising an ester moiety or a secondary amide moiety. Also provided are compositions that are synthesized using the method, as well as methods of using the compositions of the presently disclosed subject matter.
Formation of isoprostane bicyclic endoperoxides from the autoxidation of cholesteryl arachidonate
Yin, Huiyong,Havrilla, Christine M.,Morrow, Jason D.,Porter, Ned A.
, p. 7745 - 7754 (2007/10/03)
Autoxidation of polyunsaturated fatty acids and esters leads to a complex mixture containing hydroperoxides and cyclic peroxides. Prostaglandin bicyclic endoperoxides have been detected from the autoxidation of cholesteryl arachidonate by LC-MS and GC-MS
