52-44-8Relevant academic research and scientific papers
A practical approach for spiro- and 5-monoalkylated barbituric acids
Singh, Palwinder,Paul, Kamaldeep
, p. 607 - 612 (2006)
The single step reactions of N,N′- substituted/-unsubstituted barbituric acids with various alkyl dihalides under phase transfer catalytic conditions using DMF-K2CO3 (base), TBAHSO4 (catalyst) provide spirobarbituric acids
A simple synthesis of 5-spirobarbituric acids and transformations of spirocyclopropanobarbiturates to 5-substituted barbiturates
Singh, Palwinder,Paul, Kamaldeep
, p. 247 - 251 (2007/10/03)
The reactions of barbituric acid and its 1,3-dimethyl derivative with 1,2-dibromoethane, 1,4-dibromobutane, 1,5-dibromopentane and 1,2-bis[bromomethyl] benzene in DMF-K2CO3 (base), TBAHSO4 (catalyst) provide 5-spirobarbitu
