520-11-6

Usage

Uses

Used in Pharmaceutical Industry:
6-Methoxyluteolin is used as an anti-inflammatory agent for its ability to inhibit the production of pro-inflammatory cytokines, which can help in reducing inflammation in the body.
6-Methoxyluteolin is used as an antioxidant for its capacity to protect cells from oxidative damage, which can contribute to the prevention and treatment of oxidative stress-related diseases.
Used in Oncology:
6-Methoxyluteolin is used as an anticancer agent for its ability to inhibit the growth of certain cancer cells and induce apoptosis, offering potential therapeutic benefits in the treatment of various types of cancer.
Used in Drug Development:
6-Methoxyluteolin is used as a lead compound in the development of new therapeutic agents targeting inflammation, oxidative stress, and cancer, due to its multifaceted biological activities and potential for further research and formulation into effective treatments.

InChI:InChI=1/C16H12O7/c1-22-16-11(20)6-13-14(15(16)21)10(19)5-12(23-13)7-2-3-8(17)9(18)4-7/h2-6,17-18,20-21H,1H3

Upstream product

• 569-90-4 5,7,3',4'-tetrahydroxy-6-methoxyflavone-7-O-β-D-glucopyranoside 
• 88153-47-3 5,6-Dimethoxy-7,3',4'-trihydroxyflavone 

Downstream Products

• 18003-33-3 3',4',5,6,7-pentahydroxyflavone 
• 82657-12-3 C₂₂H₂₀O₁₃ 

Relevant academic research and scientific papers

New Flavonoids and Turkesterone-2-O-Cinnamate from Leaves of Rhaponticum uniflorum

Leaves of Rhaponticum uniflorum (L.) DC. (Asteraceae) afforded 46 compounds including seven new flavonoids that were identified using UV, IR, and NMR spectroscopy and mass spectrometry as 6-hydroxyluteolin-7-O-(2′-O-caffeoyl)-β-D-glucopyranoside (rhaunoside A, 1), 6-hydroxyluteolin-7-O-(6″-O-cinnamoyl)-β-D-glucopyranoside (rhaunoside B, 2), 6-hydroxyluteolin-4′-O-β-D-glucopyranoside (rhaunoside C, 3), nepetin-7-O-(6″-O-caffeoyl)-β-D-glucopyranoside (rhaunoside D, 4), nepetin-7-O-(6″-O-cinnamoyl)-β-D-glucopyranoside (rhaunoside E, 5), nepetin-3′-O-β-D-glucopyranoside (rhaunoside F, 6), and luteolin-7-O-(2″-O-caffeoyl)-β-D-glucopyranoside (rhaunoside G, 7) and the new ecdysteroid turkesterone-2-O-cinnamate (8).

Chemical constituents from cassia occidentalis Linn

The present paper deals with the isolation and structural elucidation of three new compounds 1, 2 and 3 from the seeds of Cassia occidentalis Linn. These compounds have been characterized as 5, 7-dihydroxyflavone-5-O-β-D- xylopyranosyl-7-O-α-L-rhamnopyranosyl-(1→3)-O-α-L- arabinopyranoside (1), 3, 5, 7, 3′,4′-pentahydroxy flavone-3-O-α-L-rhamnopyranosyl-7-O-β-D-glucopyranosyl-(1→3) -O-β-D-xylopyranoside (2) and 5, 7, 3′, 4′-tetrahydroxy-6- methoxyflavone-5-O-α-L-ara-binopyranosyl-(1→4)-O-α-L- rhamnopyranosyl-(1→3)-O-β-D-galactopyranoside (3) respectively by various colour reactions, chemical degradations and spectral analysis. These compounds have been evaluated against various bacteria and fungi which showed good results.

Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease

PCT No. PCT/KR97/00144 Sec. 371 Date Jan. 14, 1999 Sec. 102(e) Date Jan. 14, 1999 PCT Filed Jul. 25, 1997 PCT Pub. No. WO98/04541 PCT Pub. Date Feb. 5, 1998The present invention relates to novel flavone/flavanone compounds or their pharmaceutically acceptable salts and process for preparation thereof for protecting gastrointestinal tracts against gastritis, ulcers and inflammatory bowel disease.