52007-49-5Relevant articles and documents
Flow synthesis of secondary amines over Ag/Al2O3 catalyst by one-pot reductive amination of aldehydes with nitroarenes
Artiukha, Ekaterina A.,Nuzhdin, Alexey L.,Bukhtiyarova, Galina A.,Bukhtiyarov, Valerii I.
, p. 45856 - 45861 (2017/10/06)
An alumina-supported silver catalyst was investigated in the one-pot reductive amination of aldehydes with nitroarenes in a continuous flow reactor using molecular hydrogen as a reducing agent. A series of secondary amines containing alkyl, OH, OCH3, Cl, Br and CC groups was synthesized in good to excellent yields. The yield of the secondary amine depends on the rate of formation of an intermediate imine. It was shown that the accumulation of carbonaceous deposits on the catalyst is the main reason of catalyst deactivation. The spent catalyst can be easily regenerated and reused without losing catalytic activity.
Indium-catalyzed reduction of secondary amides with a hydrosiloxane leading to secondary amines
Sakai, Norio,Takeoka, Masashi,Kumaki, Takayuki,Asano, Hirotaka,Konakahara, Takeo,Ogiwara, Yohei
supporting information, p. 6448 - 6451 (2015/11/16)
Described herein is that the selective reduction of aromatic/aliphatic secondary amides using a combination of InI3 and TMDS (1,1,3,3-tetramethyldisiloxane), which led to the production of the corresponding secondary amines. This reducing system showed a relatively high tolerance to a variety of functional groups, such as an alkyl, an alkoxy, a halogen, a cyano, an ether, a thioether, a heterocyclic ring, and a terminal alkene group.
Insect Juvenile Hormone Analogues: Part VII - Synthesis of Long Chain Aromatic Ethers & Nitrogen Analogues
Vig, O. P.,Trehan, I. R.,Kad, G. L.,Dhawan, R. K.,Grewal, M. S.
, p. 688 - 691 (2007/10/02)
Syntheses of various aromatic ethers of undecenyl bromide and thio ethers of undecenyl and undecanyl bromides with 2-benzothiazolethiol are described.The preparation of a few amides and their corresponding amines from undecenoic acid and different aromatic amines and benzyl amine are also reported.The bromo derivatives of a few amides have also been prepared.These compounds have been tested on common Indian red cotton bug for their juvenile hormone activity.