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6-MORPHOLINO-3-PYRIDINYL ISOTHIOCYANATE, also known as CIT597, is a synthetic compound that functions as a potent inhibitor of the enzyme heat shock protein 90 (Hsp90). This enzyme is crucial for the survival and proliferation of cancer cells. CIT597 has demonstrated significant anti-cancer activity in preclinical studies, with its mechanism of action focusing on inducing apoptosis and inhibiting cancer cell growth. It holds the potential to evolve into a novel class of anti-cancer drugs, targeting a range of solid tumors and hematological malignancies. Furthermore, due to its influence on Hsp90 activity, it may also have applications in treating other diseases, including neurodegenerative disorders and autoimmune diseases.

52024-29-0

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52024-29-0 Usage

Uses

Used in Pharmaceutical Industry:
6-MORPHOLINO-3-PYRIDINYL ISOTHIOCYANATE is used as an anti-cancer agent for its ability to inhibit the enzyme Hsp90, which is essential for cancer cell survival and proliferation. It is particularly effective in inducing apoptosis and suppressing the growth of various cancer cells, making it a promising candidate for the development of new cancer treatments.
Used in Oncology Research:
In the field of oncology, 6-MORPHOLINO-3-PYRIDINYL ISOTHIOCYANATE is used as a research tool to study the role of Hsp90 in cancer cell biology. Its ability to inhibit this enzyme provides insights into the mechanisms of cancer cell survival and the potential for targeted therapies.
Used in Neurodegenerative Disorder Research:
6-MORPHOLINO-3-PYRIDINYL ISOTHIOCYANATE is used as a research compound to explore its potential in treating neurodegenerative disorders. Given the involvement of Hsp90 in these conditions, CIT597 may offer avenues for therapeutic intervention.
Used in Autoimmune Disease Research:
In autoimmune disease research, 6-MORPHOLINO-3-PYRIDINYL ISOTHIOCYANATE is utilized to investigate its impact on conditions influenced by Hsp90 activity. 6-MORPHOLINO-3-PYRIDINYL ISOTHIOCYANATE's effects on this enzyme could lead to new treatment strategies for autoimmune diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 52024-29-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,0,2 and 4 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 52024-29:
(7*5)+(6*2)+(5*0)+(4*2)+(3*4)+(2*2)+(1*9)=80
80 % 10 = 0
So 52024-29-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H11N3OS/c15-8-12-9-1-2-10(11-7-9)13-3-5-14-6-4-13/h1-2,7H,3-6H2

52024-29-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(5-Isothiocyanatopyridin-2-yl)morpholine

1.2 Other means of identification

Product number -
Other names 6-Morpholino-3-pyridinyl isothiocyanate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:52024-29-0 SDS

52024-29-0Upstream product

52024-29-0Downstream Products

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