5203-83-8Relevant academic research and scientific papers
Phospha-Michael-type reactions between 1,2-diaza-1,3-dienes and bidentate nucleophiles: Formation of new mono- and diylides and their elaboration to heterocycles
Boga, Carla,Zanna, Nicola,Attanasi, Orazio A.,Baccolini, Graziano,De Crescentini, Lucia,Forlani, Luciano,Mantellini, Fabio,Nicolini, Simona,Micheletti, Gabriele,Tozzi, Silvia
experimental part, p. 1326 - 1334 (2011/04/17)
Phospha-Michael additions of a series of methylene-bridged phosphorus bidentate nucleophiles to 1,2-diaza-1,3-dienes gave monoadducts and bisadducts in high yields under mild conditions. In particular, a series of new ylides and symmetrical diylides have been obtained from bis(diphenyl)phosphanes. The use of diphenylphosphanylamino derivatives gave, through phospha-Michael addition, ylide intermediates that underwent spontaneous intramolecular attack by the amino group belonging to the Michael donor reagent moiety, thus giving access to new heterocycles.
