52030-77-0

Upstream product

• 10574-70-6 3-(4-bromophenyl)-1,3-thiazolidine-2-thion-4-one 
• 19249-89-9 1-benzoyl-3-(4-bromophenyl)thiourea 
• 1985-12-2 4-Bromophenyl isothiocyanate 
• 598-21-0 2-Bromoacetyl bromide 

Downstream Products

• 51964-07-9 3-(4-bromo-phenyl)-5-(2-oxo-1,2-dihydro-indol-3-ylidene)-thiazolidine-2,4-dione 
• 35077-59-9 (4-bromo-phenyl)-thiazolidinetrione 5-phenylhydrazone 

Relevant academic research and scientific papers

Reaction of O-alkyl-N-substituted iminothiocarbonates with bromoacetyl bromide. A general method for the synthesis of 3-substituted 1,3-thiazolidine-2,4-diones

Reaction of sodium salts of O-methyl-N-substituted iminothiocaibonates with bromoacetyl bromide represents a new general method for preparation of 3-substituted 1,3-thiazolidine-2,4-diones in good yields and high purity. The structure of the synthesized products has been confirmed by 1H NMR, 13C NMR, IR and mass spectroscopy as well as by independent synthesis.