52059-45-7Relevant academic research and scientific papers
Arylsulfonate esters in solid phase organic synthesis. I. Cleavage with amines, thiolate, and imidazole
Rueter, Jaimie K.,Nortey, Samuel O.,Baxter, Ellen W.,Leo, Gregory C.,Reitz, Allen B.
, p. 975 - 978 (2007/10/03)
The arylsulfonate ester functionality connecting an alkyl chain to a polystyrene resin is cleaved with neat volatile primary or secondary amines to give secondary or tertiary amines, respectively, in high yields and purity. Non-volatile secondary amines, thiols, and imidazole also cleave the alkyl chain efficiently to afford the expected products which can be readily purified by an ion-exchange resin work-up method.
