52060-75-0 Usage
General Description
1-(1,2-Dioxopropyl)-L-proline, methyl ester is a chemical compound that belongs to the class of proline derivatives. It is a methyl ester of L-proline, which is an amino acid commonly found in nature. 1-(1,2-DIOXOPROPYL)-L-PROLINE, METHYL ESTER has a dioxopropyl group attached to the proline molecule, which gives it unique properties and potential applications. It is often used in the field of organic synthesis and pharmaceutical research, due to its reactivity and potential as a building block in the synthesis of more complex molecules. Additionally, it may have potential uses in the development of pharmaceutical drugs or as a research tool in biochemistry and related fields.
Check Digit Verification of cas no
The CAS Registry Mumber 52060-75-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,0,6 and 0 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 52060-75:
(7*5)+(6*2)+(5*0)+(4*6)+(3*0)+(2*7)+(1*5)=90
90 % 10 = 0
So 52060-75-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H13NO4/c1-6(11)8(12)10-5-3-4-7(10)9(13)14-2/h7H,3-5H2,1-2H3/t7-/m0/s1
52060-75-0Relevant articles and documents
Amino acids and peptides, IX. Pyruvoyl amino acids
Hausler,Schmidt
, p. 145 - 151 (1974)
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Asymmetric Catalytic Hydrogenations of N-Pyruvoyl-(S)-proline Esters
Munegumi, Toratane,Fujita, Manabu,Maruyama, Tetsuya,Shiono, Shozo,Takasaki, Michiaki,Harada, Kaoru
, p. 249 - 254 (2007/10/02)
Asymmetric catalytic hydrogenations of the entitled compounds were carried out over palladium on charcoal in various solvents to afford N--(S)-proline esters with a d.e.(=diastereoisomeric excess) of up to 59percent.The stereochemistry of the catalytic hydrogenation was explained by the "chelation mechanism." And the effects of temperature and bulkiness of the ester groups on the asymmetric induction were also described.
