52083-48-4 Usage
General Description
1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purine-7-butyric acid is a chemical compound with the molecular formula C11H16N4O4. It is a derivative of purine and is also known as theophylline acetic acid. Theophylline is a xanthine alkaloid that is used as a bronchodilator to treat symptoms of asthma, chronic bronchitis, and emphysema. It works by relaxing the muscles in the airways, which allows for easier breathing. Theophylline acetic acid is also used to treat apnea in premature infants. It is typically administered orally or through intravenous injection and is metabolized in the liver. Overall, 1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purine-7-butyric acid plays a crucial role in the management of respiratory conditions and contributes to improved lung function.
Check Digit Verification of cas no
The CAS Registry Mumber 52083-48-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,0,8 and 3 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 52083-48:
(7*5)+(6*2)+(5*0)+(4*8)+(3*3)+(2*4)+(1*8)=104
104 % 10 = 4
So 52083-48-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H14N4O4/c1-13-9-8(10(18)14(2)11(13)19)15(6-12-9)5-3-4-7(16)17/h6H,3-5H2,1-2H3,(H,16,17)/p-1
52083-48-4Relevant articles and documents
1H NMR study of the complexation of aromatic drugs with dimethylxanthine derivatives
Hernandez Santiago,Gonzalez Flores,Rosas Castilla,Cervantes Tavera,Gutierrez Perez,Khomich,Ovchinnikov,Parkes,Evstigneev
, p. 139 - 145 (2012)
With an aim of searching efficient interceptors of aromatic drugs, the self- and hetero-association of dimethylxanthine derivatives with different structures, selected according to Strategy 1 (variation of the position of methyl groups) and Strategy 2 (variation of the length of (CH2) nCOOH group), with aromatic drug molecules: Ethidium Bromide, Proflavine and Daunomycin, were studied using 1H NMR spectroscopy. It was found that the association proceeds in a form of stacking-type complexation and its energetics is relatively independent on the structure of the dimethylxanthines. However, on average, the dimethylxanthines possess higher hetero-association constant and, hence, higher interceptor ability as compared to the trimethylxanthine, Caffeine, used during the past two decades as a typical interceptor molecule.
